PPIB Protein (AA 26-216)
Quick Overview for PPIB Protein (AA 26-216) (ABIN666694)
Target
See all PPIB ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- AA 26-216
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Characteristics
- Cyclophilin B, 26- 216aa , Human, Recombinant, E.coli
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/ml (determined by Bradford assay)
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Buffer
- In 20mM Tris 8.0, .20mM NaCl, 0.5mM DTT, 10% glycerol
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Storage
- 4 °C
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- PPIB (Cyclophilin B (PPIB))
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Alternative Name
- Cyclophilin B
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Background
- Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Recombinant human cyclophilin B was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: PPIB, Peptidylprolyl isomerase B, CYPB, SCYLP, CYP-S1: Cyclophilin-B, Cyclophilin B, 26- 216aa , AA553318, AI844835, Cphn 2, Cphn2, CyP 20b, AA408962, CYP S1, MGC14109, MGC2224, peptidyl prolyl cis trans isomerase B, Peptidyl prolyl cis trans isomerase B precursor, PPIase, Rotamase, S cyclophilin. NCBI no.: NP_000933
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Molecular Weight
- 21.2kDa (192aa), confirmed by MALDI-TOF.
Target
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